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CHRONIC KIDNEY DISEASE CAUSES
Causes of
Chronic Kidney Disease
Adult
Polycystic
Kidney
Disease
The development of kidney failure is
often
in patients with adult polycystic kidney disease whose condition
has usually been diagnosed for other reasons (for instance, a
family history, hypertension, haematuria, or a loin mass).
Once kidney impairment is diagnosed, the loss of function is
predictable at about 5 to 6 ml/min per year, tending to be more
rapid in males than females.
Adult polycystic kidney disease accounts for about 6 per cent of
those receiving kidney replacement therapy in the United Kingdom
and Australia, the median age at which end-stage kidney failure
(which is not inevitable) is reached being 55 years, but with a
wide range from 25 to 75 years. End-stage kidney failure occurs
10 to 15 years later in those with type 2 adult polycystic
kidney disease than in those with the commoner type 1 disease.
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